Houston may be the top seed in the Midwest Regional, but the Cougars are in trouble against Auburn. The Cougars haven't been playing well going 1-6 ATS in their last seven games. They lost by 10 points to Memphis in the American Athletic Conference Tournament title game and only beat 16th-seeded Northern Kentucky, 63-52, this past Thursday in their first-round NCAA Tournament game. 

Star guard Marcus Sasser aggravated a groin injury against Northern Kentucky. His status is questionable. Jamal Shead, Houston's top assists player, also isn't 100 percent with a knee injury. 

Auburn is a tough opponent for the Cougars. The Tigers are playing excellent defense, not turning the ball over and are battle tested having dealt with upper tier competition being in the SEC. 

Auburn beat Iowa, 83-75, to win its 11th straight opening-round NCAA Tournament game. The Tigers took No. 1 ranked Alabama to overtime on the road and beat Tennessee by nine points during their last two regular season games. They are 6-1 ATS in their last seven NCAA Tournament games.