The Louisville Cardinals are on the road in college football action on Saturday, taking on the Boston College Eagles. The game is scheduled for a noon start time and it will be televised nationally on ESPN2. The college football odds for the game have the Cardinals favored by a comfortable margin to pick up the win.

College Football Odds
Louisville -24.5 points
Total: 55 points

The total has come down five points since the opener in this game, a battle between teams on opposite sides of the ACC standings. Louisville is 5-1 in league play and they lead the country at 50 points per game led by Lamar Jackson, the probable Heisman Trophy winner if the season were to end today.

Jackson has led the Cardinals to pile up better than 600 yards of total offense per game, they’re tied with Texas Tech at 603 yards per game atop the country.

The difference between those two teams is Louisville actually has a pretty strong defense. To be fair they haven’t played a very tough schedule and they surrendered 42 in a loss at Clemson, but outside of that the Cardinals have been holding everyone down.

Boston College is decent defensively, outside of a pair of blowouts where they gave up a combined 105 points to Virginia Tech and Clemson, the two best teams the Eagles played all season. Louisville is joining that list of the best teams Boston College has played this season and they will score points here.

Free Pick: Louisville

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Arkansas strength of schedule plus recent blowout loss handicapped by Pro Bettor Brad Powers - with RJ Bell from the Pregame.com Studios in Las Vegas. Get his NCAA Football Free Pick: Florida at Arkansas.

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