Sharpest NFL lines here, based on how often I bet into them, or rather DON'T bet into them, is definitely Cantor, then South Point and LVH. I'd hesitate to call ANY of the other books "sharp", and Wynn most certainly isn't. Also, I've cashed $6300 single tickets there and barely gotten a second look, although I play a lot of poker there too( Pro tip: if you're cashing a big amount there, but under 10k, and don't want Managerial scrutiny, wait until the Sportsbook closes and cash them at the regular casino cage. THis goes for almost all casinos, fwiw.). As far as sharpest offshore, Pinnacle is the overall sharpest obviously, but BetPro is the hardest to beat with the full -110 pricing, followed closely behind by BetCris and BetGrande...Basically anything starting with Bet is sharp, apparently...