I cant see DeVonte Holloman being a suitable replacement for Sean Lee. Lee is one of the most valuable players on the cowboys. I have him worth about -45 yards to the defense. The last matchup against the eagles he had over 10 tackles. Also Claiborne with a bum hamstring could be a problem. They cowboys are pretty Thin on defense and with the eagles being so sound at the end of the season health wise and conditioning wise I think this is their clear advantage.
Offensively The Orton -> Witten Chemistry is something i expect to see lacking. Romo relies greatly on him and they have solid timing. Dez bryant over any of the eagles corners especially Carey Williams is a huge mismatch and i think that is where the cowboys have the greatest chance to exploit. On the ground Murray is a great back but the eagles defense has been defending the run almost to perfection lately. Trent Cole has finally showed up, Demeco Ryans and Connor Barwin have been great stuffing the run and Bennie Logan and Thornton have shown great improvement. I expect Murray to be very productive in the screen game.
Eagles Offense has a distinct advantage with the dual TE threat. Neither Ertz or Celek are Top 5 Tightends but together they Provide a serious problem for Dallas's Banged up Def. Ertz vs any of the cowboys LBs is a mismatch that foles will look to exploit. Lesean Mccoys Confidence is at an all time high and he is pretty set on winning the rushing title.
The Game changer for the cowboys will be the return of Dwayne Harris and his ability to make big plays on special teams and the big plays from DEZ. I look at the eagles scoring only 3 points in there last meeting to help push this team to score more.
Eagles @ < 7.5 is my play for the game.
Also its 3am so I apologize. Please dont let my opinion change anyone's thoughts on this game these are just some Amateur views I have on this game.