I don't look at stats. There are some that have value but not many in my opinion.
I think the market is aware of all stats. There no start you will look at that the market didn't already analyze.
Best way to handicap football in my opinion is with look ahead lines and line movement.
For example team C plays team D week 2. Team C is favored by 2.5. In week 1 team C is favored by 14 and wins by 17. In week 1 team D is a 10 point underdog and loses by 7. Then you see the line change to where team C is a 3.5 point favorite after week 1. Pick team D all day.
Nothing changed but there's overreacting in the market because one team is 1-0 and the other is 0-1. Both teams did about what was expected week 1 but you still see over reaction.