504 Celtics (-10) over Pistons
In their first matchup on 12/20 the Celtics won by 21 as a 9 point home favorite and their biggest lead was by 27 and that was with one of their key players Kemba Walker scoring 2 points on 0/6 shooting from the field so this is just a bad matchup for the Pistons. The Pistons have a bottom 10 defensive rating over the last week (111.1) while the Celtics have a top 6 offensive rating over the last week (116.6). Over the last 3 years the Celtics are 8-3 SU and 6-5 ATS vs the Pistons but the Pistons are just 2-5 ATS in the last 7 meetings and 1-10 ATS in the last 11 games playing on 1 day of rest. I got the Celtics winning by 13 or more.