RB Todd Gurley is hurting but Malcolm Brown will step right in. The Rams are in position to put up or shut up as far as being an NFC Super Bowl potential rep again. Kupp, Woods & Cooks are still legit but Goff has to get them the ball and not turn it over.
The Rams Defense with Aaron Donald needs to step up as well. Extra rest is major as well. Rams played Thursday while the Niners had the Monday Night game. San Fran will be without Tackle Mike McGlinchy but more importantly, Kyle Juszczyk who makes a huge difference on the 49er offense in yards per play. Rams win by 10 plus